通信系统无源非线性引起的互调干扰

分析了通信系统中无源互调干扰产生的基本理论、产生机理、减小措施以及分析与建模，总结了无源互调干扰的探测、定位和测量方法．认为无源互调产物是多载波通信系统的重要干扰源，包括接触非线性和材料非线性在内的无源非线性是这种干扰的根本起因．目前关于无源互调幅度的分析计算还局限在幂级数方法上，今后关于无源互调问题的研究重点将是无源非线性物理模型的建立，以及由容易测量的低阶无源互调幅度预测高阶幅度更为有效方法的研究等方面．     

CODCr测定中氯离子的干扰及消除方法研究

通过实验研究氯离子对CODCr测定的干扰程度，采用硫酸汞掩蔽法，氯离子扣除法．稀释倍数法等方法去除氯离子的干扰，最终确定出处理的最佳方案是在不掩蔽氯离子条件下，对水样中氯离子产生的CODCr值进行扣除、且实验证明此种方法对实际水样同样适用。方法适用氯离子范围为0～8000mg/L。     

关于用迹表示的实矩阵的特征值的虚部的界

给出了一些用矩阵的迹表示的实矩阵的特征值的虚部的界，所得的结果推广和改进了已有文献的相应结论。     

DS-CDMA中空时多用户检测算法及其性能分析

阐述了空时多用户检测的现状，介绍和分析了空时线性多用户检测算法，盲空时多用户检测等几种主要的空时多用户检测技术，并对几种空时多用户检测方法进行了误码率仿真分析，验证了空时多用户检测可以大大改善DS-CDMA系统的性能。     

Symmetrical directional cloning: An efficient method to prepare hairpin RNA interference constructs

RNA interference (RNAi) is a loss-of-function approach by which double-stranded RNA (dsRNA) initiates degradation of homologous mRNAs in a sequence specific manner. The dsRNA molecules can be produced in vitro or in vivo, and can be introduced to cells in a number of ways. Here we report a more efficient method for the cloning of inverted repeat DNA fragments into expression vectors that can be transcribed into effective dsRNA molecules in vivo or in vitro. This method, named Symmetrical Directional Cloning (SDC), takes the advantage of compatible non-palindromic restriction enezyme sites, which allow one to directionally clone a single PCR product in both the sense and antisense orientations together into a vector. SDC allows for the directional cloning of inverted repeats using a single PCR product; it requires only one cut site on each side of the loop. Hence this method is more cost effective and less time-consuming. At least 21 commercially available restriction endonucleases can be used as cloning sites for the SDC method. The efficacy of dsRNA expression vectors prepared by SDC has been demonstrated by targeting a negative regulator of the signaling pathway mediating the response of cells to phytohormone, gibberellins (GA), in the aleurone cells.     

RNA interference-mediated inhibition of Hepatitis B Virus replication

Persistent and recurrent infection of hepatitis B virus (HBV) represents one of the most common and severe viral infections of humans, and has caused a formidable health problem in the affected countries. Currently used antiviral drugs have a very limited success on controlling HBV replication and infection. RNA interference (RNAi), a process by which double-stranded RNA (dsRNA) directs sequence-specific degradation of target mRNA in mammalian and plant cells, has recently been used to knockdown gene expression in various species. In this study, we sought to determine whether RNAi-mediated silencing of HBV viral gene expression could lead to the effective inhibition of HBV replication. We first developed RNAi vectors that expressed small interfering RNA (siRNA) and targeted the HBV core or surface gene sequence. Our results demonstrated that these specific siRNAs efficiently reduced the levels of corresponding viral RNAs and proteins, and thus suppressed viral replication. Treatment with siRNA gave the greatest reduction in the levels of HBsAg (92%) and in HBeAg (85%) respectively in the cultured cell medium. Our findings further demonstrated that the RNAi-mediated antiviral effect was sequence-specific and dose-dependent. Therefore, our findings strongly suggest that RNAi-mediated silencing of HBV viral genes could effectively inhibit the replication of HBV, hence RNAi-based strategy should be further explored as a more efficacious antiviral therapy of HBV infection.     

自适应数字波束空域相干干扰抑制方法

在干扰相干背景下,接收信号协方差矩阵中信号空间的一些向量收敛到噪声空间中,仅利用二阶信息不能准确地得到干扰的方向信息,因而干扰抑制效果较差。为此,提出了一种自适应数字波束空域相干扰抑制方法。该方法是首先基于高阶累积量估计出广义方向矢量,然后根据最优均方逼近原则,结合切比雪夫加权系数形成波束,来抑制相干干扰。仿真结果表明,所提方法能够有效地抑制相干干扰。     

透明转发器卫星通信系统在干扰条件下的互调分量

研究了有干扰时透明转发器卫星通信系统中的互调分量。首先，对有干扰时硬限幅条件下窄带系统的互调分量和DS扩频通信系统中的相关互调分量进行了理论分析；然后，针对实际系统，建立了系统仿真模型，进行了计算机性能仿真，通过对仿真结果的分析，得到一些结论。研究成果对了解透明转发器卫星通信系统在强干扰条件下存在的互调分量的影响及其量化结果，从而设计具有针对性的卫星通信抗干扰系统具有实际意义。     

阻塞矩阵方法对消主瓣干扰

当存在主瓣干扰且有期望信号混入情况下,用常规自适应波束形成方法进行自适应干扰对消,不但会引起主瓣变形,而且期望信号也会被抑制,从而影响对消性能。提出一种新的阻塞矩阵方法,对接收数据进行预处理,消除它们对计算数据协方差阵的影响,再用其它方法确定自适应权值。理论分析和计算机仿真表明,用阻塞矩阵方法可以获得较大的性能提升。     

低轨卫星辅助的干扰源位置确定

为提高针对影响同步通信卫星正常工作的地面干扰源定位精度,回避无邻近卫星无法定位问题,提出低轨卫星辅助的新方法。该方法充分利用低轨飞行所带来的长基线、近距离的好处,并以多普勒差为观测变量,卫星轨道参数为待估参数,可进一步改善定位精度。针对建立的定位数学模型进行计算,其结果显示,当低轨卫星的高度在5000km时,全区域定位精度优于1km。